通讯地址：上海市徐汇区梅陇路130号；邮编：200237
【个人简介】：
赵玉政，教授，博士生导师，北京协和医院博士生导师，上海市细胞代谢光遗传学技术前沿科学研究基地主任，中国医学科学院细胞代谢监测成像新技术创新单元主任，教育部国家级高层次人才（2021），国家重点研发计划首席科学家（2019），教育部国家级青年人才（2017），国家优秀青年科学基金获得者（2017），国家自然科学基金创新研究群体核心成员，中国细胞生物学学会细胞代谢专业委员会委员，中国生物化学与分子生物学会代谢专业委员会委员，中国细胞生物学学会衰老细胞生物学专业委员会委员，中国老年学和老年医学学会抗衰老分会委员，中国老年学和老年医学学会老年病学分会衰老基础医学专家委员会常务委员，中国抗癌协会肿瘤代谢专业委员会委员，中国医药生物技术协会神经修复与再生专业委员会委员，中国衰老标志物研究联合体专家委员会委员，中国研究型医院学会过敏医学专业委员会副主任委员，长三角现代产业学院协同育人联盟生物医药专家委员会副主任委员，上海市生物化学与分子生物学学会副理事长，上海市细胞生物学学会理事，上海市产医融合战略咨询委员会委员，上海市产医融合战略咨询委员会肿瘤治疗专业委员会委员等。
【研究方向】：
1、细胞代谢监测成像新技术开发
2、细胞代谢时空调控新机制研究
【研究生招生与博士后招聘】：
本实验室研究对象涉及基因、蛋白质、细菌、哺乳动物细胞、线虫、斑马鱼、果蝇、鼠、大动物和临床医学样本等，研究领域涉及医学、药学、药理学、细胞生物学、生物化学与分子生物学、合成生物学、光遗传学、化学遗传学、化学生物学等。我们热忱欢迎有志于从事细胞代谢研究、人类疾病诊断、创新药物开发的同学或博士加盟本实验室。
【代表性论文】（*通讯作者）：
1.Li,R.,Li,Y.,Jiang,K.,Zhang,L.,Li,T.,Zhao,A.,Zhang,Z.,Xia,Y.,Ge,K.,Chen,Y.,Wang,C.,Tang,W.,Liu,S.,Lin,X.,Song,Y.,Mei,J.,Xiao,C.,Wang,A.,Zou,Y.,Li,X.,Chen,X.,Ju,Z.,Jia,W.,Loscalzo,J.,Sun,Y.,Fang,W.*,Yang,Y.*,ZhaoY.*.Lightingupargininemetabolismrevealsitsfunctionaldiversityinphysiologyandpathology.CellMetabolism,2024,online.
3.He,J.,Wang,A.,Zhao,Q.,Zou,Y.,Zhang,Z.,Sha,N.,Hou,G.,Zhou,B.,Yang,Y.,Chen,T.,Zhao,Y.*,Jiang,Y.*.RNAiscreensidentifyHES4asaregulatorofredoxbalancesupportingpyrimidinesynthesisandtumorgrowth.NatureStructural&MolecularBiology,2024,31(9),1413-1425.
4.Zhao,Y.*,Jiang,Y.*.HES4controlsredoxbalanceandsupportspyrimidinesynthesisandtumorgrowth.NatureStructural&MolecularBiology,2024,31(9),1315-1316.
5.Li,X.,Zhang,Y.,Xu,L.,Wang,A.,Zou,Y.,Li,T.,Huang,L.,Chen,W.,Liu,S.,Jiang,K.,Zhang,X.,Wang,D.,Zhang,L.,Zhang,Z.,Zhang,Z.,Chen,X.,Jia,W.,Zhao,A.,Yan,X.,Zhou,H.,Zhu,L.,Ma,X.,Ju,Z.,Jia,W.,Wang,C.*,Loscalzo,J.,Yang,Y.*,Zhao,Y.*.Ultrasensitivesensorsrevealthespatiotemporallandscapeoflactatemetabolisminphysiologyanddisease.CellMetabolism,2023,35(1),200-211.
6.Dou,X.,Fu,D.,Long,Q.,Liu,S.,Zou,Y.,Fu,D.,Xu,Q.,JiangZ.,Ren,X.,Zhang,G.,WeiX.,LiQ.,Campisi,J.,Zhao,Y.*,SunY.*.PDK4-dependenthypercatabolismandlactateproductionofsenescentcellspromotescancermalignancy.NatureMetabolism,2023,5,1887-1910.
7.Jia,M.,Yue,X.,Sun,W.,Zhou,Q.,Chang,C.,Gong,W.,Feng,J.,Li,X.,Zhan,R.,Mo,K.,Zhang,L.,Qian,Y.,Sun,Y.,Wang,A.,Zou,Y.,Chen,W.,Li,Y.,Huang,L.,Yang,Y.*,Zhao,Y.*,Cheng,X.*.ULK1-mediatedmetabolicreprogrammingregulatesVps34lipidkinaseactivitybyitslactylation.ScienceAdvances,2023,9,eadg4993.
8.Huang,D.,Zhang,C.,Xiao,M.,Li,X.,Chen,W.,Jiang,Y.,Yuan,Y.,Zhang,Y.,Zou,Y.,Deng,L.,Wang,Y.,Sun,Y.,Dong,W.,Zhang,Z.,Xie,L.,Yu,Z.,Chen,C.,Liu,L.,Wang,J.,Yang,Y.*,Yang,J.*,Zhao,Y.*,Zheng,J.*.RedoxmetabolismmaintainstheleukemogeniccapacityanddrugresistanceofAMLcells.PNAS,2023,120(13),e2210796120.
9.Chen,C.*,Lai,X.,Xie,L.,Yu,Z.,Dan,S.,Jiang,Y.,Chen,W.,Liu,L.,Yang,Y.,Zhang,Y.,Huang,D.*,Zhao,Y.*,ZhengJ.*.NADPHmetabolismdeterminestheleukemogeniccapacityanddrugresistanceofAMLcells.CellReports,2022,39(1),110607.
10.Ma,C.,ZhengK.,Jiang,K.,Zhao,Q.,Sha,N.,Wang,W.,Yan,M.,Chen,T.,Zhao,Y.*,Jiang,Y.*.ThealternativeactivityofnuclearPHGDHcontributestotumorgrowthundernutrientstress.NatureMetabolism,2021,3(10),1357-1371.
11.Chen,C.,HaoX.,LaiX.,LiuL.,ZhuJ.,ShaoH.,HuangD.,GuH.,ZhangT.,YuZ.,XieL.,ZhangX.,YangY.,XuJ.*,ZhaoY.*,LuZ.*,ZhengJ.*.OxidativephosphorylationenhancestheleukemogeniccapacityandresistancetochemotherapyofB-cellacutelymphoblasticleukemia.ScienceAdvances,2021,7,eabd6280.
12.Zou,Y.,Wang,A.,Huang,L.,Zhu,X.,Hu,Q.,Zhang,Y.,Chen,X.,Li,F.,Wang,Q.,Wang,H.,Liu,R.,Zuo,F.,Li,T.,Yao,J.,Qian,Y.,Shi,M.,Yue,X.,Chen,W.,Zhang,Z.,Wang,C.,Zhou,Y.,Zhu,L.,Ju,Z.,Loscalzo,J.,Yang,Y.*,Zhao,Y.*.IlluminatingNAD+metabolisminlivecellsandinvivousingageneticallyencodedfluorescentsensor.DevelopmentalCell,2020,53(2),240-252.
13.Gu,H.,Chen,C.,Hao,X.,Su,N.,Huang,Dan.,Zou,Y.,Lin,S.,Chen,X.,Zheng,D.,Liu,L.,Yu,Z.,Xie,L.,Zhang,Y.,He,X.,Lai,X.,Zhang,X.,Chen,G.,Zhao,Y.*,Yang,Y.*,Loscalzo,J.,Zheng,J.*.MDH1-mediatedmalate-aspartateNADHshuttlemaintainstheactivitylevelsoffetalliverhematopoieticstemcells.Blood,2020,136(5),553-571.
14.Zou,Y.,Wang,A.,Shi,M.,Chen,X.,Liu,R.,Li,T.,Zhang,C.,Zhang,Z.,Zhu,L.,Ju,Z.,Loscalzo,J.,Yang,Y.*,Zhao,Y.*.Analysisofredoxlandscapesanddynamicsinlivingcellsandinvivousinggeneticallyencodeduorescentsensors.NatureProtocols,2018,13(10),2362-2386.
15.Tao,R.#,Zhao,Y.#,Chu,H.#,Wang,A.,Zhu,J.,Chen,X.,Zou,Y.,Shi,M.,Liu,R.,Su,N.,Du,J.,Zhou,H.,Zhu,L.,Qian,X.,Liu,H.,Loscalzo,J.,andYang,Y.GeneticallyencodedfluorescentsensorsrevealdynamicregulationofNADPHmetabolism.NatureMethods,2017,14(7),720-728.
16.Zhao,Y.,Wang,A.,Zou,Y.,Su,N.,Loscalzo,J.,andYang,Y.InvivomonitoringofcellularenergymetabolismusingSoNar,ahighlyresponsivesensorforNAD+/NADHredoxstate.NatureProtocols,2016,11(8),1345-1359.(CoverStory)
17.Zhao,Y.,Hu,Q.,Cheng,F.,Su,N.,Wang,A.,Zou,Y.,Hu,H.,Chen,X.,Zhou,H.,Huang,X.,Yang,K.,Zhu,Q.,Wang,X.,Yi,J.,Zhu,L.,Qian,X.,Chen,L.,Tang,Y.,Loscalzo,J.,andYang,Y.SoNar,ahighlyresponsiveNAD+/NADHsensor,allowshigh-throughputmetabolicscreeningofanti-tumoragents.CellMetabolism,2015,21(5),777-789.
18.Zhao,Y.,Jin,J.,Hu,Q.,Zhou,H.M.,Yi,J.,Yu,Z.,Xu,L.,Wang,X.,Yang,Y.,andLoscalzo,J.GeneticallyencodedfluorescentsensorsforintracellularNADHdetection.CellMetabolism,2011,14(4),555-566.
【综述著作】（*通讯作者）：
1.Zhang,Z.,Chen,C.,Li,X.,Zheng,J.*,Zhao,Y.*.Regulationofleukemogenesisviaredoxmetabolism.TrendsinCellBiology,2024,34(11),928-941.
2.Li,X.*,Wen,X.,Tang,W.,Wang,C.,Chen,Y.,Yang,Y.,Zhang,Z.*,Zhao,Y.*.Elucidatingthespatiotemporaldynamicsofglucosemetabolismwithgeneticallyencodedfluorescentbiosensors.CellReportsMethods,2024,4(11),100904.
4.RenJ.,SongM.,ZhangW.,CaiJ.,CaoF.,CaoZ.,ChanP.,ChenC.,ChenG.,ChenH.,ChenJ.,ChenX.,CiW.,DingB.,DingQ.,GaoF.,GaoS.,HanJ.,HeQ.,HuangK.,JuZ.,KongQ.,LiJ.,LiJ.,LiJ.,LiX.,LiuB.,LiuF.,LiuJ.,LiuL.,LiuQ.,LiuQ.,LiuX.,LiuY.,LuoX.,MaS.,MaX.,MaoZ.,NieJ.,PengY.,QuJ.,RenR.,SongW.,SongyangZ.,SunL.,SunY.E.,SunY.,TianM.,TianX.,TianY.,WangJ.,WangS.,WangS.,WangW.,WangX.,WangX.,WangY.,WangY.,WongC.,XiangA.P.,XiaoY.,XiaoZ.,XieZ.,XiongW.,XuD.,YangZ.,YeJ.,YuW.,YueR.,ZhangC.,ZhangH.,ZhangL.,ZhangX.,ZhangY.,ZhangY.,ZhangZ.,ZhaoT.,ZhaoY.,ZhouZ.,ZhuD.,ZouW.,PeiG.,LiuG.TheAgingBiomarkerConsortiumrepresentsaneweraforagingresearchinChina.NatureMedicine,2023,29,pages2162–2165.
5.Chen,W.,Liu,S.,Yang,Y.,Zhang,Z.*,Zhao,Y.*.SpatiotemporalMonitoringofNAD+MetabolismwithFluorescentBiosensors.MechanismsofAgeingandDevelopment,2022,204,111657.
6.Li,T.,Zou,Y.,Liu,S.,Yang,Y.,Zhang,Z.*,Zhao,Y.*.MonitoringNAD(H)andNADP(H)dynamicsduringorganismaldevelopmentwithgeneticallyencodedfluorescentbiosensors.CellRegeneration,2022,11,5.
7.Zhang,Z.,Cheng,X.,Zhao,Y.*,Yang,Y.*.Lightinguplive-cellandinvivocentralcarbonmetabolismwithgeneticallyencodedfluorescentsensors.AnnualReviewofAnalyticalChemistry,2020,13,293-314.
8.Zhang,Z.,Chen,W.,Zhao,Y.*,Yang,Y.*.Spatiotemporalimagingofcellularenergymetabolismwithgenetically-encodedfluorescentsensorsinbrain.NeuroscienceBulletin,2018,34(5),875-886.
9.Zhao,Y.*,Zhang,Z.,Zou,Y.,Yang,Y.*.Visualizationofnicotineadeninedinucleotideredoxhomeostasiswithgeneticallyencodedfluorescentsensors,Antioxidants&RedoxSignaling,2018,28(3),213-229.
10.Zhao,Y.*,Zhang,Z.,Yang,Y.*.Monitoringintracellularredoxmetabolismwithgeneticallyencodedfluorescentsensors.ScientiaSinicaVitae,2017,47:508-521.
11.Zhao,Y.*,Yang,Y.*.Real-timeandhigh-throughputanalysisofmitochondrialmetabolicstatesinlivingcellsusinggeneticallyencodedNAD+/NADHsensors.FreeRadicalBiology&Medicine,2016,100,43-52.
12.Zhao,Y.,Yang,Y.*.ProfilingmetabolicstateswithgeneticallyencodedfluorescentbiosensorsforNADH.CurrentOpinioninBiotechnology,2015,31,86-92.
13.Zhao,Y.,Yang,Y.,andLoscalzo,J.Real-TimeAssessmentoftheMetabolicProfileofLivingCellswithGeneticallyEncodedNADHSensors.MethodsinEnzymology,2014,542,349-367.(ISBN：978-0-12-416618-9)
【部分合作论文】：
1.ZuoF,JiangL,SuN,ZhangY,BaoB,WangL,ShiY,YangH,HuangX,LiR,ZengQ,ChenZ,LinQ,ZhuangY,ZhaoY,ChenX,ZhuL,YangY.ImagingthedynamicsofmessengerRNAwithabrightandstablegreenfluorescentRNA.NatureChemicalBiology,2024,20(10),1272-1281.
2.ZouJ,JiangK,ChenY,MaY,XiaC,DingW,YaoM,LinY,ChenY,ZhaoY*,GaoF*.Tofacitinibcitratecoordination-baseddual-responsive/scavengenanoplatformtowardregulatecolonicinflammatorymicroenvironmentforrelievingcolitis.AdvancedHealthcareMaterials,2024,2401869.
3.BaiL,WangY,WangK,ChenX,ZhaoY,LiuC,QuX.MateriobiomodulatedROStherapyfordenovohairgrowth.AdvancedMaterials,2024,36,2311459.
4.WengL,TangW,WangX,GongY,LiuC,HongN,TaoY,LiK,LiuS,JiangW,LiY,YaoK,ChenL,HuangH,ZhaoY,HuZ,LuY,YeH,DuX,ZhouH,LiP,ZhaoT.Surplusfattyacidsynthesisincreasesoxidativestressinadipocytesandinduceslipodystrophy.NatureCommunications,2024,15,133.
5.LiJ,HouW,ZhaoQ,HanW,CuiH,XiaoS,ZhuL,QuJ,LiuX,CongW,ShenJ,ZhaoY,GaoS,HuangG,KongQ.LactateregulatesmajorzygoticgenomeactivationbyH3K18lactylationinmammals.NationalScienceReview,2024,11,nwad295.
6.JiangL,XieX,SuN,ZhangD,ChenX,XuX,ZhangB,HuangK,YuJ,FangM,BaoB,ZuoF,YangL,ZhangR,LiH,HuangX,ChenZ,ZengQ,LiuR,LinQ,ZhaoY,RenA,ZhuL,YangY.LargeStokesshiftfluorescentRNAsfordual-emissionfluorescenceandbioluminescenceimaginginlivecells.NatureMethods,2023,20,1563-1572.
7.ZhangD.,ChenZ.,DuZ.,BaoB.,SuN.,ChenX.,GeY.,LinQ.,YangL.,HuaY.,WangS.,HuaX.,ZuoF.,LiN.,LiuR.,JiangL.,BaoC.,ZhaoY.,LoscalzoJ.,YangY.,ZhuL.DesignofapaletteofSNAP-tagmimicsoffluorescentproteinsandtheiruseascellreporters.CellDiscovery,2023,9,56.
8.SunH.,ZhangZ.,LiT.,LiTing,ChenW.,PanT.,FangS.,LiuC.,ZhangY.,WangL.,FengG.,LiW.,ZhouQ.*,ZhaoY.*.Live-cellimagingrevealsredoxmetabolicreprogrammingduringzygoticgenomeactivation.JournalofCellularPhysiology,2023,238(9),2039-2049.
9.HeM.,SunYu.,ChengY.,WangJ.,ZhangM.,SunR.,HouX.,XuJ.,HeH.,WangH.,YuanZ.,LanM.,ZhaoY.,YangY.,ChenX.,GaoF.Spatiotemporallycontrollablediphtherintransgenesystemandneoantigenimmunotherapy.JournalofControlledRelease,2023,355,538-551
10.FangM.,LiH.,XieX.,WangH.,JiangY.,LiT.,ZhangB.,JiangX.,CaoY.,ZhangR.,ZhangD.,ZhaoY.,ZhuL.,ChenX.,YangY.ImagingintracellularmetaboliteandproteinchangesinlivemammaliancellswithbrightfluorescentRNA-basedgeneticallyencodedsensors.BiosensorsandBioelectronics,2023,235,115411.
11.Liu,R.,Yang,J.,Yao,J.,Zhao,Z.,He,W.,Su,N.,Zhang,Z.,Zhang,C.,Zhang,Z.,Cai,H.,Zhu,L.,Zhao,Y.,Quan,S.,Chen,X.,Yang.Y.OptogeneticcontrolofRNAfunctionandmetabolismusingengineeredlight-switchableRNA-bindingprotein.NatureBiotechnology,2022,40,779-786.
12.ZhaoJ.,YaoK.,YuH.,ZhangL.,XuY.,ChenL.,SunZ.,ZhuY.,ZhangC.,QianY.,JiS.,PanH.,ZhangM.,ChenJ.,CorreiaC.,WeiskittelT.,LinD.W.,ZhaoY.,ChandrasekaranS.,FuX.,ZhangD.,FanH.Y.,XieW.,LiH.,HuZ.,ZhangJ.Metabolicremodellingduringearlymouseembryodevelopment.NatureMetabolism,2021,3,1372-1384.
13.HeX.,WanJ.,YangX.,ZhangX.,HuangD.,LiX.,ZouY.,ChenC.,YuZ.,XieL.,ZhangY.,LiuL.,LiS.,ZhaoY.,ShaoH.,YuY.,ZhengJ.BonemarrownicheATPlevelsdetermineleukemia-initiatingcellactivityviaP2X7inleukemicmodels.JournalofClinicalInvestigation,2021,131(4),e140242.
14.LiT.,ChenX.,QianY.,ShaoJ.,LiX.,LiuS,ZhuL.,ZhaoY.,YeH.,Yang.Y.AsyntheticBRET-basedoptogeneticdeviceforpulsatiletransgeneexpressionenablingglucosehomeostasisinmice.NatureCommunications,2021,12,615.
15.Liu,K.,Guo,C.,Lao,Y.,Yang,J.,Chen,F.,Zhao,Y.,Yang,Y.,Yang,J.,Yi,J.Afine-tuningmechanismunderlyingself-controlforautophagy:deSUMOylationofBECN1bySENP3.Autophagy,2020,16(6),975-990.
16.Li,X.,Zhang,C.,Xu,X.,Miao,J.,Yao,J.,Liu,R.,Zhao,Y.,Chen,X.,YangY.Asingle-componentlightsensorsystemallowshighlytunableanddirectactivationofgeneexpressioninbacterialcells.NucleicAcidsResearch,2020,48(6),e33.
17.Chen,X.,Zhang,D.,Su,N.,Bao,B.,Xie,X.,Zuo,F.,Yang,L.,Wang,H.,Jiang,L.,Lin,Q.,Fang,M.,Li,N.,Hua,X.,Chen,Z.,Bao,C.,Xu,J.,Du,W.,Zhang,L.,Zhao,Y.,Zhu,L.,Loscalzo,J.,Yang,Y.VisualizingRNAdynamicsinlivecellswithbrightandstablefluorescentRNAs.NatureBiotechnology,2019,37(11),1287-1293.
18.Hao,X.,Gu,H.,Chen,C.,Huang,D.,Zhao,Y.,Xie,L.,Zou,Y.,Shu,H.,Zhang,Y.,He,X.,Lai,X.,Zhang,X.,Zhou,B.,Zhang,C.,Chen,G.,Yu,Z.,Yang,Y.,Zheng,J.Metabolicimagingrevealsauniquepreferenceofsymmetriccelldivisionandhomingofleukemia-Initiatingcellsinanendostealniche.CellMetabolism,2019,29(4),950-965.
19.Cheng,F.,Lu,W.,Liu,C.,Fang,J.,Hou,Y.,Handy,D.,Wang,R.,Zhao,Y.,Yang,Y.,Huang,J.,Hill,D.,Vidal,M.,Eng,C.,Loscalzo,J.Agenome-widepositioningsystemsnetworkalgorithmforinsilicodrugrepurposing.NatureCommunications,2019,10,3476.
20.Zhu,X.,Shen,W.,Yao,K.,Wang,H.,LiuB.,Li,T.,Song,L.,Diao,D.,Mao,G.,Huang,P.,Li,C.,Zhang,H.,Zou,Y.,Qiu,Y.,Zhao,Y.,Wang,W.,Yang,Y.,Hu,Z.,Auwerx,J.,Loscalzo,J.,Zhou,Y.,Ju,Z.Fine-tuningofPGC1αexpressionregulatescardiacfunctionandlongevity.CirculationResearch,2019,125(7),707-719.
21.Liu,X.,Zhang,F.,Zhang,Y.,Li,X.,Chen,C.,Zhou,M.,Yu.Z.,Liu,Y.,Zhao,Y.,Hao,X.,Tang,Y.,Zhu,L.,Liu,L.,Xie,L.,Gu,H.,Shao,H.,Xia,F.,Yin,C.,Tao,M.,Xie,J.,Zhang,C.,Yang,Y.,Sun,H.,Chen,G.,Zheng,J.PPM1KregulateshematopoiesisandleukemogenesisthroughCDC20-mediatedubiquitinationofMEIS1andp21.CellReports,2018,23,1461-1475.
22.Chen,X.,Tian,M.,Sun,R.,Zhang,M.,Zhou,L.,Jin,L.,Chen,L.,Zhou,W.,Duan,K.,Chen,Y.,Gao,C.,Cheng,Z.,Wang,F.,Zhang,J.,Sun,Y.,Yu,H.,Zhao,Y.,Yang,Y.,Liu,W.,Shi,Y.,Xiong,Y.,Guan,K.,andYe,D.SIRT5inhibitsperoxisomalACOX1topreventoxidativedamageandisdownregulatedinlivercancer.EMBOReports,2018,e45124.
23.Fang,Y.,Liu,Z.,Chen,Z.,Xu,X.,Xiao,M.,Yu,Y.,Zhang,Y.,Zhang,X.,Du,Y.,Jiang,C.,Zhao,Y.,Wang,Y.,Fan,B.,Terheyden-Keighley,D.,Liu,Y.,Shi,L.,Hui,Y.,Zhang,X.,Zhang,B.,Feng,H.,Ma,L.,Zhang,Q.,Jin,G.,Yang,Y.,Xiang,B.,Liu,L.,Zhang,X.Smad5actsasanintracellularpHmessengerandmaintainsbioenergetichomoeostasis.CellResearch,2017,27,1083-1099.
24.Yang,K.,Wang,M.,Zhao,Y.,Sun,X.,Yang,Y.,Li,X.,Zhou,A.,Chu,H.,Zhou,H.,Xu,J.,Wu,M.,Yang,J.,andYi,J.Aredoxmechanismunderlyingnucleolarstresssensingbynucleophosmin.NatureCommunications,2016,7,13599.
25.Yang,H.,Zhou,L.,Shi,Q.,Zhao,Y.,Lin,H.,Zhang,M.,Zhao,S.,Yang,Y.,Ling,Z.,Guan,K.,Xiong,Y.,andYe,D.SIRT3-dependentGOT2acetylationstatusaffectsthemalate-aspartateNADHshuttleactivityandpancreatictumorgrowth.EMBOJournal,2015,34,1110-1125.
26.Wang,Y.,Zhou,L.,Zhao,Y.,Wang,S.,Chen,L.,Liu,L.,Ling,Z.,Hu,F.,Sun,Y.,Zhang,J.,Yang,C.,Yang,Y.,Xiong,Y.,Guan,K.,andYe,D.RegulationofG6PDacetylationbySIRT2andKAT9modulatesNADPHhomeostasisandcellsurvivalduringoxidativestress.EMBOJournal,2014,33,1304–1320.