1.转化医学网4663内容 0关注 4833粉丝 转化医学核心门户 上海 更多信息 【Nature子刊】大连医科大学顾春东教授团队:肺癌肿瘤干细胞精准治疗潜在靶点 2024-12-21 15:22 【Cell】肿瘤抑制基因新发现:KEAP1合性成为肺癌预测的关键生物标志物 2024-12-21 15:21 【Nature子刊】复旦大学附属浦东医院王晓亮团队重磅发现:SLC50A1成肝癌新https://www.163.com/dy/media/T1608556126673.html

2.最新!elife解除onhold!2023年10月,Science News指出,执行新政之后,eLife发表周期明显缩短,但投稿量也出现下降。 2024年10月,eLife被科睿唯安列入“on hold”名单。 我们来看一下eLife的相关信息 http://weixin.qq.com/r/QROvtzjE62WUrXzU90ZT (二维码自动识别) http://weixin.qq.com/r/QROvtzjE62WUrXzU90ZT (二维码自动识别)https://zhuanlan.zhihu.com/p/13511682414

3.CrisprGE:acentralhubofCRISPR/CasTherefore, we have developed CrisprGE, a central hub of CRISPR/Cas-based genome editing. Presently, this database holds a total of 4680 entries of 223 unique genes from 32 model and other organisms. It encompasses information about the organism, gene, target gene sequences, genetic modificationhttps://www.ncbi.nlm.nih.gov/m/pubmed/26120138/

4.CRISPRhomepageHome page CRISPRs database CRISPRs finder CRISPRs comparison Tools MyCRISPRdb BLAST CRISPRdb CRISPRcompar CRISPRtionary FlankAlign CRISPRs Utilities GPMS Links GPMS Team Tandem Repeats DB MLVA Web Service External Links Tandem Repeats Finder GenomesOnline Cas Genes at TIGR CRISPRhttps://crispr.i2bc.paris-saclay.fr/

5.CRISPRGE:AConvenientSoftwareToolkitforCRISPRCrisprGE: a central hub of CRISPR/Cas-based genome editing CRISPR system is a powerful defense mechanism in bacteria and archaea to provide immunity against viruses. Recently, this process found a new application in intended targeting of the genomes. CRISPR-mediated genome editing is performed b.https://xueshu.baidu.com/usercenter/paper/show?paperid=2af36cb68f18bbce7cd3038515b90ee6

6.CRISPR/Cas9therapeutics:progressandprospectsSignalClustered regularly interspaced short palindromic repeats (CRISPR)/CRISPR-associated protein 9 (Cas9) gene-editing technology is the ideal tool of the future for treating diseases by permanently correcting deleterious base mutations or disrupting disease-causing genes with great precision and efficiency. Ahttps://www.nature.com/articles/s41392-023-01309-7

7.ComputationalToolsandResourcesforCRISPR/CasGenomeCRISPR-GE > 40 plant species SpCas9, FnCpf1, and AsCpf1 Providing software toolkits, primer design for vector construction, on-target amplification, and PCR sequencing result analysis Web server https://skl.scau.edu.cn/ [94] CRISPR-P 49 plant species > 14 Cas9 and variants Supporting widehttps://www.sciencedirect.com/science/article/pii/S1672022922000274

8.Science:FeiChen团队基因编辑领域新突破,新工具首次实现靶向区「Helicase-assisted continuous editing for programmable mutagenesis of endogenous genomes」(图 1),该研究报道了他们最新开发的对哺乳动物细胞内源性基因组进行靶向诱变的技术--解旋酶介导的连续突变技术(Helicaseassisted continuous editinghttps://mp.weixin.qq.com/s?__biz=MzUxMzk5MjY5NA==&mid=2247635881&idx=2&sn=48f4075bc1e2b1beb773f69cf913e2f7&chksm=f8385faddcd3228e128d034fd0131f2acaf74d9add7754c235c4f42025d7e474e6dee8e81c5b&scene=27

9.NewPlantBreedingTechniquesinCitrusfortheImprovement(www.crispr.hzau.edu. cn/cgi-bin/CRISPR2/CRISPR), CRISPRdirect (www.crispr.dbcls. jp), Chop-Chop (www.chopchop.cbu.uib.no), E-CRISPR (www.e- crisp.org), CRISPR-GE (www.crdd.osdd.net/servers/crisprge), CRISPR RGEN Tools (http://www.rgenome.net), and CRISPOR (http://www.https://www.frontiersin.org/articles/10.3389/fpls.2020.01234/pdf